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Andrew M. Schurko, Ph.D.
Postdoctoral Fellow (Logsdon Lab) Department of Biological Sciences Roy J. Carver Center for Comparative Genomics Iowa City, Iowa 52242 Ph: 319-335-1083 e-mail: andrew-schurko_at_uiowa.edu |
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Education:
Ph.D. (Microbiology) 2003, University of Manitoba, Winnipeg, Manitoba, Canada
B.Sc (Hons) 1997, University of Manitoba
My Research:
I use degenerate PCR and database-mining to survey genomes for genes involved in meiosis and other cellular processes. Currently, my research focuses on three main projects:
1) Meiotic genes and ancient asexuals.
Bdelloid rotifers (microscopic animals) are the best-studied "ancient asexuals"; evidence suggests that they have survived and flourished for at least 100 million years without having sex!
I use degenerate PCR to amplify meiosis-specific genes from bdelloid and sexual monogonont genomes. The absence of meiotic genes is consistent with ancient asexuality; the presence of meiotic genes would suggest the capacity for meiosis and possibly sex!
2) Cohesin protein evolution.
Cohesin is a multi-subunit complex involved in sister-chromatid cohesion during mitosis and meiosis. Using database-mining and degenerate PCR, I am studying the evolution of meiosis-specific components of cohesin (e.g. Rec8, Scc3) in protists and insects.
3) Assembling the Tree of Life
As part of the ATOL project, our lab is involved in reconstructing the phylogeny of the Tree of Life, with a focus on protists and the root of the tree (see Eu-Tree link for more info). My main interest is in the opisthokonts and relationships among animals, fungi, and protist lineages within.
Publications:
Bedard, J.E.J., Schurko, A.M., de Cock, A.W.A.M. and Klassen, G.R. 2006. Diversity and evolution of 5S rRNA gene family organization in Pythium. Mycological Research 110:86-95.
Fernando, W.G.G., Zhang, J.X., Chen, C.Q., Remphrey, W.R., Schurko, A.M. and Klassen, G.R. 2005. Molecular and morphological characteristics of Apiosporina morbosa, the causal agent of black knot in Prunus spp. Canadian Journal of Plant Pathology 27:364-375.
Li, Y., Kelly, W. G., Logsdon, Jr., J.M., Schurko, A.M., Harfe, B. D., Hill-Harfe, K. L. and Kahn, R. A. 2004. Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans. FASEB Journal, 18:1834-1850. [PDF]
Iranpour, M., Schurko, A.M., Klassen, G.R., and Galloway, T.D. 2004. DNA fingerprinting of adult tabanids (Diptera: Tabanidae) and their respective egg masses using PCR-restriction fragment profiling. The Canadian Entomologist 136:605-619.
Schurko, A.M., Mendoza, L., de Cock, A.W.A.M., Bedard, J.E.J., and Klassen, G.R. 2004. Development of a species-specific probe for Pythium insidiosum and the diagnosis of pythiosis. Journal of Clinical Microbiology 42:2411-2418.
Schurko, A.M., Mendoza L., Lévesque, C.A., Désaulniers, N.L., de Cock, A.W.A.M., and Klassen G.R. 2003. A molecular phylogeny of Pythium insidiosum. Mycological Research 107: 537-544.
Schurko, A.M., Mendoza, L., de Cock, A.W.A.M., and Klassen, G.R. 2003. Evidence for geographic clusters: Molecular genetic differences among strains of Pythium insidiosum from Asia, Australia, and the Americas are explored. Mycologia 95:200-208.
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